You can reset the number of available internal mix busses in your session to match your system’s full capabilities by reverting to the default bus configuration.
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Resetting busses to the default setting will rename all busses to their default name (Bus 1–2, Bus 3–4, and so on).The Bus page of the I/O Setup displays the number of active internal mix busses. If the number of active busses exceeds the number of available busses (256), the display turns red. Delete or deactivate any active busses in excess of the available number of busses to be able close the I/O Setup and save your settings.